Found 49 matching trials
Effects of Titrated Oral Tolvaptan 15-60 mg Once Daily (QD) on Cognitive and Neurological Function in Elderly Hyponatremic Patients
PHASE3Demonstrate an improvement in the composite scores of validated neurocognit...
Location
Sarah. S. Olelewe, MD
Dose Exploring and Setting Study for Tolvaptan to Treat Hepatic Cirrhosis With Ascites
PHASE2To observe the safety/efficacy of tolvaptan for treatment of patients with ...
Location
Renji hospital, Shanghai Jiaotong University School of Medicine
A Dose-finding Study of OPC-41061 in Treatment of Cardiac Edema (Congestive Heart Failure)
PHASE2This drug is being developed to treat cardiac edema. The primary purpose of...
Location
Otsuka Pharmaceutical Co., Ltd.
The Use of Tolvaptan to Prevent Renal Dysfunction in High Risk Patients With Heart Failure-Pilot Study
PHASE4It is well known that the use of loop diuretics in acute setting may decrea...
Location
University of Michigan Health Systems
A Double-blind, Placebo-controlled Study of OPC-41061 in the Treatment of Cardiac Edema (Congestive Heart Failure)
PHASE3To evaluate the efficacy and safety of 7-day repeated oral administration o...
Location
Multiple Locations
EVEREST: Efficacy of Vasopressin Antagonism in hEart failuRE: Outcome Study With Tolvaptan
PHASE3The purpose of this study is to compare the effectiveness of tolvaptan or p...
Location
University of Alabama at Birmingham
The Role of Vasopressin Antagonism on Renal Sodium Handling
PHASE1Vasopressin has primarily been considered to be a water and osmosis regulat...
Location
Multiple Locations
Effect of Tolvaptan on Mid- to Long-term Prognosis of Heart Failure Patients
PHASE4One tolvaptan 15 mg tablet or placebo tablet will be orally administered on...
Location
Multiple Locations
Tolvaptan to Reduce Length of Stay in Hospitalized Patients With Cirrhosis and Hyponatremia
PHASE4Hyponatremia is a condition in which there is a low sodium level in the blo...
Location
NYU Langone Medical Center
Tolvaptan-Octreotide LAR Combination in ADPKD
PHASE2Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a leading cause of ...
Location
CRC per le Malattie Rare Aldo e Cele Daccò